The Bionanophotonics team was created in 2006 with the mission to conduct studies located at the interface between physics and life sciences. Our experimental biophysical approach to study complex biological systems is based on monitoring interaction of light with biological material through microscopic and spectroscopic techniques. The objectives defined within our collaborations with several biological teams and clinicians in the region are to better understand the molecular and cellular mechanisms involved in diseases such as cancer and neuropathy in order to propose new therapeutic approaches. The combination of advanced imaging techniques with molecular detection afforded by a novel generation of photonic biosensors is the strengths of our team addressing hereby the theme diagnosis and the follow-up therapy recognized of high importance by the international biomedical community.
The biophysical studies are performed in our laboratory comprising several original techniques :
Optical waveguide lightmode spectroscopy
Infrared spectroscopy in attenuated total reflexion mode
Inverted optical microscope (Nikon-TE2000) also working in epi-fluorescence and differential interference (Nomarski) contrast mode
Atomic Force microscopy (MFP3D-Asylum Research) mounted on an inverted optical microscope (Olympus) also working in epi-fluorescence and phase contrast
Multiphotonique microscope (mounted on a Zeiss microscope) working in two-photon excited fluorescence and second harmonic generation
The two main scientific themes we are developing are the photonics for bioimaging and photonic biosensing.