(1) Presentation(s)
Mer. 24/01/2024 09:45 Bâtiment 20, Amphi HEINER Zsuzsanna (Humboldt-Universität zu Berlin) Interfacial macromolecular folding and interactions from in situ nonlinear vibrational spectroscopy (Bio Nano Imagerie) Many important processes in chemistry and biology occur at interfaces where the molecular interactions and dynamics significantly differ from those observed in the bulk. Proper characterization of the behavior of peptides and proteins at macromolecular interfaces, including their reversible adsorption to surfaces and their folding into the membrane, is a prerequisite for understanding fundamental physiological processes stemming from intracellular reactions. A powerful noninvasive, optical, surface analytical tool is vibrational sum frequency generation (VSFG) spectroscopy, which often enables direct observation of the structural and dynamical properties of interfacial molecules. Nevertheless, the acquisition times and spectral resolution of traditional broadband VSFG spectrometers are far from ideal to follow the interaction of macromolecules at bio-interfaces in real-time and in situ. Pour plus d'informations, merci de contacter Finco A. |