Jeu. 15/02/2018 11:00 Grande Ourse, Bâtiment 13, Etage 1
WALLISER Nils-ole (Laboratoire Charles Coulomb)
Looping and Clustering: a statistical physics approach to protein-DNA complexes in bacteria
The DNA shows a high degree of spatial and dynamical organization over a broad range of length scales. It interacts with different populations of proteins and can form protein-DNA complexes that underlie various biological processes, including chromosome segregation. A prominent example is the large ParB-DNA complex, an essential component of a widely spread mechanism for DNA segregation in bacteria. Recent studies suggest that DNA-bound ParB proteins interact with each other and condense into large clusters with multiple extruding DNA-loops.
Pour plus d'informations, merci de contacter Parmeggiani A.