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(12) Production(s) de l'année 2018
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Cerebrospinal Fluid, MRI, and Florbetaben-PET in Cerebral Amyloid Angiopathy-Related Inflammation
Auteur(s): Renard Dimitri, Collombier Laurent, Demattei Christophe, Wacongne Anne, Charif Mahmoud, Ayrignac Xavier, Azakri Souhayla, Gaillard Nicolas, Boudousq Vincent, Lehmann Sylvain, Menjot De Champfleur N., Thouvenot Eric
(Article) Publié:
Journal Of Alzheimer's Disease, vol. 61 p.1107 - 1117 (2018)
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Pineal Anaplastic Ependymoma With Multifocal Intradural Extramedullary Metastases on MRI and 18FDG-PET
Auteur(s): Ben Bouallègue Fayçal, Vauchot Fabien, Menjot De Champfleur N., Mariano-Goulart Denis
(Article) Publié:
Clinical Nuclear Medicine, vol. 43 p.e319 - e321 (2018)
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Transient immediate postoperative homotopic functional disconnectivity in low-grade glioma patients
Auteur(s): Coget Arthur, Deverdun J., Bonafé Alain, Dokkum Liesjet, Duffau Hugues, Molino F., Le Bars E., Menjot De Champfleur N.
(Article) Publié:
Neuroimage: Clinical, vol. 18 p.656-662 (2018)
Texte intégral en Openaccess :
Ref HAL: hal-02071081_v1
DOI: 10.1016/j.nicl.2018.02.023
WoS: 000433169000068
Exporter : BibTex | endNote
3 Citations
Résumé: Background and purposeThe aim of this longitudinal study is to evaluate large-scale perioperative resting state networks reorganization in patients with diffuse low-grade gliomas following awake surgery.Materials and methodsEighty-two patients with diffuse low-grade gliomas were prospectively enrolled and underwent awake surgical resection. Resting-state functional images were acquired at three time points: preoperative (MRI-1), immediate postoperative (MRI-2) and three months after surgery (MRI-3). We simultaneously performed perfusion-weighted imaging.
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Modified Brain Activations of the Nondamaged Hemisphere During Ipsilesional Upper-Limb Movement in Persons With Initial Severe Motor Deficits Poststroke.
Auteur(s): van Dokkum Liesjet E H, Le Bars E., Mottet Denis, Bonafé Alain, Menjot De Champfleur N., Laffont Isabelle
(Article) Publié:
Neurorehabilitation And Neural Repair, vol. 32 p.34-45 (2018)
Texte intégral en Openaccess :
Ref HAL: hal-01727594_v1
PMID 29276841
DOI: 10.1177/1545968317746783
WoS: 000425064200004
Exporter : BibTex | endNote
3 Citations
Résumé: Poststroke, the ipsilesional upper limb shows slight but substantial and long-term motor deficits.;To define brain activation patterns during a gross motor flexion/extension task of the ipsilesional elbow early poststroke before and after rehabilitation, in relation to the corresponding kinematic characteristics at each time point.;Simultaneous analysis of kinematic features (amplitude, frequency, smoothness, and trajectory of movement) and of corresponding functional magnetic resonance imaging activations (block-design). A total of 21 persons with subacute initial severe stroke (Fugl-Meyer score <30/66) participated twice: within the first 2 months poststroke (V0) and after 6 weeks of rehabilitation (V1). Results at both time points were compared with activation patterns and kinematics of 13 healthy controls.;Compared with controls ( a) movements of the ipsilesional upper-limb poststroke were smaller (V0 + V1) and less smooth (V0 + V1) and ( b) participants poststroke showed additional recruitment of the contralesional middle temporal gyrus (V0) and rolandic opercularis involved in movement visualization (V0 + V1), whereas they lacked activation of the supramarginal gyrus (V0 + V1). Over time, participants poststroke showed an extended activation of the contralesional sensorimotor cortex at V0.;Movements of the ipsilesional upper limb within an initially severe stroke group were not only atypical in motor outcome, but seemed to be controlled differently. Together the observed changes pointed toward an overall disturbance of the bihemispheric motor network poststroke, marked by ( a) a possible despecialization of the nondamaged hemisphere and ( b) the employment of alternative control strategies to ensure optimal task execution.
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Is impaired cerebral vasoreactivity an early marker of cognitive decline in multiple sclerosis patients?
Auteur(s): Metzger Aude, Le Bars E., Deverdun J., Molino F., Maréchal Bénédicte, Picot Marie-Christine, Ayrignac Xavier, Carra Clarisse, Bauchet Luc, Krainik Alexandre, Labauge Pierre, Menjot De Champfleur N.
(Article) Publié:
European Journal Of Radiology, vol. 28 p.1204-1214 (2018)
Ref HAL: hal-01727597_v1
PMID 29026971
DOI: 10.1007/s00330-017-5068-5
WoS: 000424997600034
Exporter : BibTex | endNote
8 Citations
Résumé: The link between cerebral vasoreactivity and cognitive status in multiple sclerosis remains unclear. The aim of the present study was to investigate a potential decrease of cerebral vasoreactivity in multiple sclerosis patients and correlate it with cognitive status.;Thirty-three patients with multiple sclerosis (nine progressive and 24 remitting forms, median age: 39 years, 12 males) and 22 controls underwent MRI with a hypercapnic challenge to assess cerebral vasoreactivity and a neuropsychological assessment. Cerebral vasoreactivity, measured as the cerebral blood flow percent increase normalised by end-tidal carbon dioxide variation, was assessed globally and by regions of interest using the blood oxygen level-dependent technique. Non-parametric statistics tests were used to assess differences between groups, and associations were estimated using linear models.;;Cognitive impairment in multiple sclerosis may be mediated through decreased cerebral vasoreactivity. Cerebral vasoreactivity could therefore be considered as a marker of cognitive decline in multiple sclerosis.;• Cerebral vasoreactivity does not differ between multiple sclerosis patients and controls. • Cerebral vasoreactivity measure is linked to cognitive impairment in multiple sclerosis. • Cerebral vasoreactivity is linked to level of education in multiple sclerosis.
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